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Diseases

Giant Cell Tumor of Bone

giant cell tumor of bone

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Giant Cell Tumor of Bone
Standard Disease Name
giant cell tumor of bone
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D018212
OMIM ID
No data
UMLS ID
C0206638
HPO ID
No data

Description and Extensions

Description
NCI2016_02D:A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.|MSH2017_2016_08_12:A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)|HPO2016_07_04:A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. [HPO:probinson]
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
02
BRAF
B-Raf proto-oncogene, serine/threonine kinase
B-Raf proto-oncogene, serine/threonine kinase
07
NR3C1
nuclear receptor subfamily 3 group C member 1
nuclear receptor subfamily 3 group C member 1
08
RUNX3
RUNX family transcription factor 3
RUNX family transcription factor 3