01
- Entity Type
- Diseases
- Relation Groups
- 1
- Relation Preview
- 8
Basic Information
Grouped by core information, identifiers, and descriptions.
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Core Information
- Disease Name
- Long Qt Syndrome
- Standard Disease Name
- long qt syndrome
- MeSH Tree
- No data
- ICD-10
- I45.81
Identifiers
- DO ID
- No data
- MeSH ID
- D008133
- OMIM ID
- MTHU039019
- UMLS ID
- C0023976
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NICHD_1602D:A syndrome characterized by a propensity to develop life-threatening arrhythmias usually in the context of a prolonged corrected QT interval.|NCI2016_CDISC_1602D:Long QT Syndrome includes prolongation of the corrected QT interval beyond 440 ms for adult males, 460 ms for adult females and 50 ms in the presence of ventricular depolarization abnormalities (i.e., bundle branch blocks or IVCB more than 120 ms. A normal QT interval in a resting ECG with a failure to shorten with an increase in heart rate qualifies as Long QT Syndrome.|NCI2016_02D:A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death.|MSH2017_2016_08_12:A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.|CSP2006:prolongation of Q-T interval combined with torsades de pointes and manifests as several different forms; may be acquired or congenital; may lead to serious arrhythmia and sudden cardiac death.
Related
Related Entities
Direct relations and traceable candidates grouped by relation type.
Related Targets
target disease8 Targets
02
KCNE2
No data
03
KCNE3
No data
04
KCNH2
potassium voltage-gated channel subfamily H member 2
potassium voltage-gated channel subfamily H member 2
05
KCNJ11
potassium inwardly rectifying channel subfamily J member 11
potassium inwardly rectifying channel subfamily J member 11
06
KCNQ1
potassium voltage-gated channel subfamily Q member 1
potassium voltage-gated channel subfamily Q member 1
07
08