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- Entity Type
- Diseases
- Relation Groups
- 4
- Relation Preview
- 32
Basic Information
Grouped by core information, identifiers, and descriptions.
Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.
Core Information
- Disease Name
- Dysgerminoma
- Standard Disease Name
- dysgerminoma
- MeSH Tree
- No data
- ICD-10
- No data
Identifiers
- DO ID
- No data
- MeSH ID
- D004407
- OMIM ID
- MTHU034594
- UMLS ID
- C0013377
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NCI-GLOSS_1602D:A type of tumor that begins in the type of cells that give rise to egg cells and is most often found in the ovaries. Dysgerminomas may also occur in other places in the body, including the central nervous system. They are the most common type of ovarian germ cell tumor and can spread to other parts of the body. They are most common in females who are younger than 20 years old.|NCI2016_CDISC_1602D:A malignant germ cell neoplasm characterized by the presence of a monotonous primitive germ cell population, primarily in the ovary.|NCI2016_02D:A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage.|MSH2017_2016_08_12:A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)|HPO2016_07_04:The presence of a dysgerminoma, i.e., an undifferentiated germ cell tumor of the ovary. [HPO:sdoelken]
Related
Related Entities
Direct relations and traceable candidates grouped by relation type.
Candidate Ingredients
target disease -> ingredient target8 Ingredients
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