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BZW1
No data
- Entity Type
- Diseases
- Relation Groups
- 2
- Relation Preview
- 16
Basic Information
Grouped by core information, identifiers, and descriptions.
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Core Information
- Disease Name
- Melanoma
- Standard Disease Name
- melanoma
- MeSH Tree
- No data
- ICD-10
- No data
Identifiers
- DO ID
- No data
- MeSH ID
- D008545
- OMIM ID
- MTHU000127|MTHU001388
- UMLS ID
- C0025202
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NICHD_1602D:A malignant neoplasm comprised of melanocytes typically arising in the skin.|NCI2016_NCI-GLOSS_1602D:A form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines.|NCI2016_CDISC_1602D:A malignant neoplasm composed of melanocytes.|NCI2016_02D:A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.|MSH2017_2016_08_12:A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)|MEDLINEPLUS_20151021:<p>Melanoma is the most serious type of <a href='https://www.nlm.nih.gov/medlineplus/skincancer.html'>skin cancer</a>. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or "ugly looking."</p> <p>Thinking of "ABCDE" can help you remember what to watch for:</p> <ul> <li> Asymmetry - the shape of one half does not match the other</li> <li> Border - the edges are ragged, blurred or irregular</li> <li> Color - the color is uneven and may include shades of black, brown and tan</li> <li> Diameter - there is a change in size, usually an increase</li> <li>Evolving - the mole has changed over the past few weeks or months</li> </ul> <p>Surgery is the first treatment of all stages of melanoma. Other treatments include chemotherapy and radiation, biologic, and targeted therapies. Biologic therapy boosts your body's own ability to fight cancer. Targeted therapy uses substances that attack cancer cells without harming normal cells.</p> <p >NIH: National Cancer Institute</p>|HPO2016_07_04:The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea). [HPO:probinson]|HPO2016_07_04:The presence of a melanoma of the skin. [HPO:probinson]|CSP2006:malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites; occurring mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo; frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved.
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