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Diseases

Leukomalacia, Periventricular

leukomalacia, periventricular

Entity Type
Diseases
Relation Groups
3
Relation Preview
24

Basic Information

Grouped by core information, identifiers, and descriptions.

Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.

Core Information

Disease Name
Leukomalacia, Periventricular
Standard Disease Name
leukomalacia, periventricular
MeSH Tree
No data
ICD-10
P91.2

Identifiers

DO ID
No data
MeSH ID
D007969
OMIM ID
MTHU037926|MTHU033878|MTHU038753
UMLS ID
C0023529
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:A form of cerebral white matter injury usually seen in preterm infants that is characterized by necrotic degeneration or gliosis of white matter adjacent to the cerebral ventricles, that may evolve into focal cysts.|NCI2016_02D:Necrosis and softening of the white matter around the ventricles in the brain. It is usually seen in preterm infants and caused by lack of blood flow and oxygenation in the periventricular brain parenchyma.|MSH2017_2016_08_12:Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
03
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit
ERCC excision repair 2, TFIIH core complex helicase subunit
04
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit
ERCC excision repair 3, TFIIH core complex helicase subunit