Diseases

Retinitis Pigmentosa 11

retinitis pigmentosa 11

Entity Type: Diseases
Relation Groups: 3
Relation Preview: 24

Basic Information

Grouped by core information, identifiers, and descriptions.

Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.

Core Information

Disease Name: Retinitis Pigmentosa 11
Standard Disease Name: retinitis pigmentosa 11
MeSH Tree: No data
ICD-10: No data

Identifiers

DO ID: No data
MeSH ID: No data
OMIM ID: 147050
UMLS ID: C0020523|C0236175|C1840253|C1840254|C1840253
HPO ID: No data

Description and Extensions

Description: NCI2016_NICHD_1602D:An immunoglobulin E (IgE) mediated hypersensitivity reaction. These usually occur within an hour of exposure to an allergen.|NCI2016_02D:Immediate hypersensitivity reaction - type I reaction, involves immunoglobulin E (IgE)-mediated release of chemical mediators from mast cells and basophils. Th2 cells produce IL-4 and IL-13, which then act on B cells to promote the production of antigen-specific IgE. Reexposure to the antigen can then result in the antigen binding to and cross-linking the bound IgE antibodies on the mast cells and basophils. This causes the release of preformed mediators (histamine, tryptase, tryptase, chemotactic factors), newly synthesized mediators (leukotrienes, prostaglandin, thromboxane, platelet-activating factor, adenosine, bradykinin), and cytokines from these cells that results in structural and functional changes to the affected tissue.|MSH2017_2016_08_12:Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.|GO2016_05_01:An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. [GOC:add, ISBN:0781735149]|CSP2006:hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.

Direct relations and traceable candidates grouped by relation type.