01
- Entity Type
- Diseases
- Relation Groups
- 3
- Relation Preview
- 24
Basic Information
Grouped by core information, identifiers, and descriptions.
Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.
Core Information
- Disease Name
- Motor Neuron Disease
- Standard Disease Name
- motor neuron disease
- MeSH Tree
- No data
- ICD-10
- G12.2|G12.20
Identifiers
- DO ID
- No data
- MeSH ID
- D016472
- OMIM ID
- MTHU036400
- UMLS ID
- C0085084
- HPO ID
- No data
Description and Extensions
- Description
- MSH2017_2016_08_12:Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)|CSP2006:disorders of motor neurons which result in atrophy, fasciculation and fibrillations, spasticity, decreased muscle tone, loss of or overactive tendon reflexes, and abnormal extensor reflexes.
Related
Related Entities
Direct relations and traceable candidates grouped by relation type.
Candidate Ingredients
target disease -> ingredient target8 Ingredients
02
()-Bornyl Acetate
No data
03
04
()-Cuparene
No data
05
06
(+)-(Z)-Methyl epijasmonate
No data
07
08
(+)-Anomalin
No data