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Diseases

Malignant hyperpyrexia due to anesthesia

malignant hyperpyrexia due to anesthesia

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Malignant hyperpyrexia due to anesthesia
Standard Disease Name
malignant hyperpyrexia due to anesthesia
MeSH Tree
No data
ICD-10
T88.3

Identifiers

DO ID
No data
MeSH ID
D008305
OMIM ID
145600|MTHU023121|180901
UMLS ID
C0024591
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:A rare drug reaction characterized by a rapid rise of the body temperature and rhabdomyolysis.|NCI2016_02D:A rare disorder characterized by rapid rise of the body temperature, accompanied by rhabdomyolysis and, if untreated, by collapse and death. It occurs in susceptible individuals who receive certain drugs for general anesthesia, gas anesthetics, or succinylcholine. It may be inherited in an autosomal dominant pattern.|MSH2017_2016_08_12:Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.|HPO2016_07_04:Malignant hyperthermia is characterized by a rapid increase in temperature to 39-42 degrees C in response to inhalational anesthetics such as halothane or to muscle relaxants such as succinylcholine. [HPO:curators]|CSP2006:usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
01
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
cholinergic receptor nicotinic alpha 1 subunit
03
GYPB
glycophorin B (MNS blood group)
glycophorin B (MNS blood group)
04
KCNA1
potassium voltage-gated channel subfamily A member 1
potassium voltage-gated channel subfamily A member 1
06
RUNX2
RUNX family transcription factor 2
RUNX family transcription factor 2
07
SCN4A
sodium voltage-gated channel alpha subunit 4
sodium voltage-gated channel alpha subunit 4
08
SCN5A
sodium voltage-gated channel alpha subunit 5
sodium voltage-gated channel alpha subunit 5