Diseases

Peripheral Arterial Diseases

peripheral arterial diseases

Entity Type: Diseases
Relation Groups: 3
Relation Preview: 24

Basic Information

Grouped by core information, identifiers, and descriptions.

Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.

Core Information

Disease Name: Peripheral Arterial Diseases
Standard Disease Name: peripheral arterial diseases
MeSH Tree: No data
ICD-10: No data

Identifiers

DO ID: No data
MeSH ID: D058729
OMIM ID: No data
UMLS ID: C1704436
HPO ID: No data

Description and Extensions

Description: NCI2016_02D:A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest.|MSH2017_2016_08_12:Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.|MEDLINEPLUS_20151021:Peripheral arterial disease (PAD) happens when there is a narrowing of the blood vessels outside of your heart. The cause of PAD is <a href='https://www.nlm.nih.gov/medlineplus/atherosclerosis.html'>atherosclerosis</a>. This happens when plaque builds up on the walls of the arteries that supply blood to the arms and legs. Plaque is a substance made up of fat and cholesterol. It causes the arteries to narrow or become blocked. This can reduce or stop blood flow, usually to the legs. If severe enough, blocked blood flow can cause tissue death and can sometimes lead to amputation of the foot or leg. The main risk factor for PAD is smoking. Other risk factors include older age and diseases like diabetes, high blood cholesterol, high blood pressure, heart disease, and stroke. Many people who have PAD don't have any symptoms. If you have symptoms, they may include <ul> <li>Pain, numbness, achiness, or heaviness in the leg muscles. This happens when walking or climbing stairs.</li> <li>Weak or absent pulses in the legs or feet</li> <li>Sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all</li> <li>A pale or bluish color to the skin</li> <li>A lower temperature in one leg than the other leg</li> <li>Poor nail growth on the toes and decreased hair growth on the legs</li> <li>Erectile dysfunction, especially among men who have diabetes</li> </ul> PAD can increase your risk of <a href='https://www.nlm.nih.gov/medlineplus/heartattack.html'>heart attack</a>, <a href='https://www.nlm.nih.gov/medlineplus/stroke.html'>stroke</a>, and <a href='https://www.nlm.nih.gov/medlineplus/transientischemicattack.html'>transient ischemic attack</a>. Doctors diagnose PAD with a physical exam and heart and imaging tests. Treatments include lifestyle changes, medicines, and sometimes surgery. Lifestyle changes include dietary changes, exercise, and efforts to lower high <a href='https://www.nlm.nih.gov/medlineplus/cholesterol.html'>cholesterol</a> levels and <a href='https://www.nlm.nih.gov/medlineplus/highbloodpressure.html'>high blood pressure</a>. NIH: National Heart, Lung, and Blood Institute

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