Diseases

Dementia, Lewy Body

dementia, lewy body

Entity Type: Diseases
Relation Groups: 3
Relation Preview: 24

Basic Information

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Core Information

Disease Name: Dementia, Lewy Body
Standard Disease Name: dementia, lewy body
MeSH Tree: No data
ICD-10: No data

Identifiers

DO ID: No data
MeSH ID: No data
OMIM ID: 127750
UMLS ID: C0752347|C1851957|C1851958
HPO ID: No data

Description and Extensions

Description: PSY2004:Neurodegenerative disease marked by the presence of Lewy body cells in the cerebral cortex and brain stem. Symptoms often include dementia, parkinsonianism, and striking fluctuations in cognitive performance.|NCI2016_02D:A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and loss of cholinergic and dopaminergic neurons. The signs and symptoms overlap with Alzheimer and Parkinson disease.|MSH2017_2016_08_12:A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)|MEDLINEPLUS_20151021:Lewy body disease is one of the most common causes of <a href='https://www.nlm.nih.gov/medlineplus/dementia.html'>dementia</a> in the elderly. Dementia is the loss of mental functions severe enough to affect normal activities and relationships. Lewy body disease happens when abnormal structures, called Lewy bodies, build up in areas of the brain. The disease may cause a wide range of symptoms, including <ul> <li>Changes in alertness and attention</li> <li>Hallucinations</li> <li>Problems with movement and posture</li> <li>Muscle stiffness</li> <li>Confusion</li> <li>Loss of memory</li> </ul> Lewy body disease can be hard to diagnose, because <a href='https://www.nlm.nih.gov/medlineplus/parkinsonsdisease.html'>Parkinson's disease</a> and <a href='https://www.nlm.nih.gov/medlineplus/alzheimersdisease.html'>Alzheimer's disease</a> cause similar symptoms. Scientists think that Lewy body disease might be related to these diseases, or that they sometimes happen together. Lewy body disease usually begins between the ages of 50 and 85. The disease gets worse over time. There is no cure. Treatment focuses on drugs to help symptoms. NIH: National Institute of Neurological Disorders and Stroke

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