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Diseases

Multiple Acyl Coenzyme A Dehydrogenase Deficiency

multiple acyl coenzyme a dehydrogenase deficiency

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Standard Disease Name
multiple acyl coenzyme a dehydrogenase deficiency
MeSH Tree
No data
ICD-10
E71.313

Identifiers

DO ID
No data
MeSH ID
D054069
OMIM ID
231680
UMLS ID
C0268596
HPO ID
No data

Description and Extensions

Description
NCI2016_02D:A rare autosomal recessive inherited metabolic disorder caused by mutations in the ETFA, ETFB, or ETFDH genes. It is characterized by deficiency of the enzyme electron transfer flavoprotein or the enzyme electron transfer flavoprotein dehydrogenase. It results in metabolic acidosis, hypoglycemia, and behavioral changes. Additional abnormalities include brain malformations, facial malformations, dilated cardiomyopathy, and hepatomegaly.|NCI2016_02D:A rare autosomal recessive inherited metabolic disorder caused by mutations in the ETFA, ETFB, and ETFDH genes. It is characterized by defects of the electron transfer flavoprotein or electron transfer flavoprotein dehydrogenase. Clinical presentations include congenital abnormalities, hepatomegaly, metabolic acidosis, and hypotonia.|MSH2017_2016_08_12:An autosomal recessive disorder of fatty acid oxidation, and branched chain amino acids (AMINO ACIDS, BRANCHED-CHAIN); LYSINE; and CHOLINE catabolism, that is due to defects in either subunit of ELECTRON TRANSFER FLAVOPROTEIN or its dehydrogenase, electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1).
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
05
ETFDH
electron transfer flavoprotein dehydrogenase
electron transfer flavoprotein dehydrogenase
06
SLPI
secretory leukocyte peptidase inhibitor
secretory leukocyte peptidase inhibitor
07
SMN1
survival of motor neuron 1, telomeric
survival of motor neuron 1, telomeric