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Diseases

Acral Lentiginous Malignant Melanoma

acral lentiginous malignant melanoma

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Acral Lentiginous Malignant Melanoma
Standard Disease Name
acral lentiginous malignant melanoma
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
No data
OMIM ID
No data
UMLS ID
C0346037
HPO ID
No data

Description and Extensions

Description
NCI2016_02D:A form of melanoma occurring most often on the plantar, palmar, subungual, and periungual skin. It presents as a pigmented macular lesion with irregular borders. Morphologically, it consists of atypical spindled and dendritic melanocytes. The epidermis is often hyperplastic and there is pagetoid infiltration of the epidermis by anaplastic cells.|HPO2016_07_04:A type of cutaneous melanoma localized to the palm, sole, or beneath the nail (subungual melanoma). Acral lentiginous melanoma starts as a slowly-enlarging flat patch of discoloured skin and usually displays a size above 6 mm and often several centimetres or more in diameter upon diagnosis and variable pigmentation with a mixutre of colors including brown, and blue-grey, black and red. The surface of the lesion is initially smooth but later in the course may become thicker and irregular, and may ulcerate or bleed. [HPO:probinson]
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
01
BRAF
B-Raf proto-oncogene, serine/threonine kinase
B-Raf proto-oncogene, serine/threonine kinase
02
CDKN2A
cyclin dependent kinase inhibitor 2A
cyclin dependent kinase inhibitor 2A
04
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
major histocompatibility complex, class II, DQ alpha 1
07
TERT
telomerase reverse transcriptase
telomerase reverse transcriptase