01
- Entity Type
- Diseases
- Relation Groups
- 1
- Relation Preview
- 8
Basic Information
Grouped by core information, identifiers, and descriptions.
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Core Information
- Disease Name
- Cushing Syndrome
- Standard Disease Name
- cushing syndrome
- MeSH Tree
- No data
- ICD-10
- E24|E24.9
Identifiers
- DO ID
- No data
- MeSH ID
- D003480
- OMIM ID
- MTHU016145
- UMLS ID
- C0010481
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NICHD_1602D:A constellation of signs and symptoms associated with abnormally high levels of cortisol in the body. It may be characterized by central obesity, hypertension, abnormal glucose tolerance, and other physical findings.|NCI2016_NCI-GLOSS_1602D:A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the body. Cushing syndrome may be caused by taking too many steroid drugs or by certain types of tumors. Tumors that make adrenocorticotropic hormone (ACTH) cause the adrenal gland to make too much cortisol. Symptoms of Cushing syndrome include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure, high blood sugar, purple or pink stretch marks on the skin, and weight gain, especially in the abdomen.|NCI2016_02D:A syndrome caused by high levels of cortisol in the blood either due to excessive production and secretion of corticosteroids secondary to pituitary or adrenocortical neoplasms, or intake of glucocorticoid drugs. Signs and symptoms include a round face, upper body obesity, fragile and thin skin, purple stretch marks in the skin, fatigue, muscle weakness, hypertension, diabetes mellitus, hypertrichosis and amenorrhea in women, impotence in men, and osteoporosis.|MSH2017_2016_08_12:A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.|MEDLINEPLUS_20151021:<p>Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland makes. Sometimes, taking synthetic hormone medicine to treat an inflammatory disease leads to Cushing's. Some kinds of tumors produce a hormone that can cause your body to make too much cortisol.</p> <p>Cushing's syndrome is rare. Some symptoms are</p> <ul> <li>Upper body obesity </li> <li>Thin arms and legs</li> <li>Severe fatigue and muscle weakness</li> <li>High blood pressure</li> <li>High blood sugar</li> <li>Easy bruising</li> </ul> <p>Lab tests can show if you have it and find the cause. Your treatment will depend on why you have too much cortisol. If it is because you have been taking synthetic hormones, a lower dose may control your symptoms. If the cause is a tumor, surgery and other therapies may be needed.</p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|CSP2006:condition, more commonly seen in females, due to hyperadrenocorticism resulting from neoplasms of the adrenal cortex or the anterior lobe of the pituitary, or to prolonged excessive intake of glucocorticoids for therapeutic purposes; symptoms and signs may include rapidly developing adiposity of the face, neck, and trunk, kyphosis caused by osteoporosis of the spine, hypertension, diabetes mellitus, amenorrhea, hypertrichosis in females, impotence in males, dusky complexion with purple markings, polycythemia, pain in the abdomen and back, and muscular wasting and weakness.|CHV2011_02:a rare hormonal disease that occurs when the body produces too much of the hormone cortisol|CHV2011_02:a rare hormonal disease that occurs when the body produces too much of the hormone cortisol