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Diseases

Cataplexy

cataplexy

Entity Type
Diseases
Relation Groups
2
Relation Preview
16

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Cataplexy
Standard Disease Name
cataplexy
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D002385
OMIM ID
MTHU003011|161400
UMLS ID
C0007384
HPO ID
No data

Description and Extensions

Description
PSY2004:Temporary loss of muscle tone or weakness following extreme emotion.|NCI2016_02D:A rare disorder characterized by sudden and transient episodes of loss of muscle tone. It often follows an experience of intense emotions. It is seen in patients with narcolepsy.|MSH2017_2016_08_12:A condition characterized by transient weakness or paralysis of somatic musculature triggered by an emotional stimulus or physical exertion. Cataplexy is frequently associated with NARCOLEPSY. During a cataplectic attack, there is a marked reduction in muscle tone similar to the normal physiologic hypotonia that accompanies rapid eye movement sleep (SLEEP, REM). (From Adams et al., Principles of Neurology, 6th ed, p396)|HPO2016_07_04:A sudden and transient episode of bilateral loss of muscle tone, often triggered by emotions. [HPO:probinson, pmid:21931493, pmid:22249574]|CSP2006:transient attack of weakness precipitated by emotional excitement; patient falls as if struck down.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
04
KCNA1
potassium voltage-gated channel subfamily A member 1
potassium voltage-gated channel subfamily A member 1
05
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
potassium calcium-activated channel subfamily M alpha 1
08
UGCG
UDP-glucose ceramide glucosyltransferase
UDP-glucose ceramide glucosyltransferase