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Diseases

Hypogonadotropic Hypogonadism

hypogonadotropic hypogonadism

Entity Type
Diseases
Relation Groups
2
Relation Preview
16

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Hypogonadotropic Hypogonadism
Standard Disease Name
hypogonadotropic hypogonadism
MeSH Tree
No data
ICD-10
E23.0

Identifiers

DO ID
No data
MeSH ID
D007006
OMIM ID
MTHU004823|MTHU041808|MTHU038027|MTHU037332
UMLS ID
C0271623
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:Insufficient production of estrogen or testosterone in the ovaries or testes due to decreased secretion of gonadotropins as a result of pituitary or hypothalamus gland dysfunction.|NCI2016_02D:Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.(NICHD)|HPO2016_07_04:Hypogonadotropic hypogonadism is characterized by reduced function of the gonads (testes in males or ovaries in females) and results from the absence of the gonadal stimulating pituitary hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH). [HPO:curators]|HPO2016_07_04:A reduced ability to secrete gonadotropins, which are protein hormones secreted by gonadotrope cells of the anterior pituitary gland, including the hormones follitropin (FSH) and luteinizing hormone (LH). [DDD:spark]
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
02
BRAF
B-Raf proto-oncogene, serine/threonine kinase
B-Raf proto-oncogene, serine/threonine kinase
05
NR5A1
nuclear receptor subfamily 5 group A member 1
nuclear receptor subfamily 5 group A member 1
07
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1
SOS Ras/Rac guanine nucleotide exchange factor 1