Diseases

Otosclerosis

otosclerosis

Basic Information

Grouped by core information, identifiers, and descriptions.

Quick relations do not expand inferred candidates by default. Load path-derived ingredients or herbs when needed.

Description: MSH2017_2016_08_12:Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.|HPO2016_07_04:In otosclerosis, a callus of bone accumulates on the stapes creating a partial fixation. This limits the movement of the stapes bone, which results in hearing loss. [HPO:probinson, pmid:15931303]|CSP2006:pathological condition of the bony labyrinth of the ear, in which there is formation of spongy bone; may cause bony ankylosis of the stapes, resulting in conductive hearing loss; cochlear otosclerosis may also develop, resulting in sensorineural hearing loss.

Direct relations and traceable candidates grouped by relation type.