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Core Information
Disease Name
Gastroesophageal Reflux Disease
Standard Disease Name
gastroesophageal reflux disease
MeSH Tree
No data
ICD-10
K21.9|K21
Identifiers
DO ID
No data
MeSH ID
D005764
OMIM ID
MTHU001906|109350|MTHU002522
UMLS ID
C0017168
HPO ID
No data
Description and Extensions
Description
NCI2016_NICHD_1602D:Reflux of stomach contents with symptoms and/or complications from the reflux act.|NCI2016_NCI-GLOSS_1602D:The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach).|NCI2016_CTCAE_1602D:A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion.|NCI2016_02D:A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa.|MSH2017_2016_08_12:Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.|MEDLINEPLUS_20151021:<p>Your esophagus is the tube that carries food from your mouth to your stomach. Gastroesophageal reflux disease (GERD) happens when a muscle at the end of your esophagus does not close properly. This allows stomach contents to leak back, or reflux, into the esophagus and irritate it. </p> <p>You may feel a burning in the chest or throat called <a href='https://www.nlm.nih.gov/medlineplus/heartburn.html'>heartburn</a>. Sometimes, you can taste stomach fluid in the back of the mouth. If you have these symptoms more than twice a week, you may have GERD. You can also have GERD without having heartburn. Your symptoms could include a dry cough, asthma symptoms, or trouble swallowing.</p> <p>Anyone, including infants and children, can have GERD. If not treated, it can lead to more serious health problems. In some cases, you might need medicines or surgery. However, many people can improve their symptoms by</p> <ul> <li>Avoiding alcohol and spicy, fatty or acidic foods that trigger heartburn</li> <li>Eating smaller meals</li> <li>Not eating close to bedtime </li> <li>Losing weight if needed </li> <li>Wearing loose-fitting clothes</li> </ul> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:A condition in which the stomach contents leak backwards from the stomach into the esophagus through the lower esophageal sphincter. [HPO:probinson]
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