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Diseases

Prion Diseases

prion diseases

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Prion Diseases
Standard Disease Name
prion diseases
MeSH Tree
No data
ICD-10
A81.9

Identifiers

DO ID
No data
MeSH ID
D017096
OMIM ID
No data
UMLS ID
C0162534
HPO ID
No data

Description and Extensions

Description
MSH2017_2016_08_12:A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)|CSP2006:any of various brain diseases in humans and animals in which areas of the brain slowly degenerate and take on a spongy appearance.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
06
MAPT
microtubule associated protein tau
microtubule associated protein tau
08
PDK1
pyruvate dehydrogenase kinase 1
pyruvate dehydrogenase kinase 1