01
- Entity Type
- Diseases
- Relation Groups
- 1
- Relation Preview
- 8
Basic Information
Grouped by core information, identifiers, and descriptions.
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Core Information
- Disease Name
- Addison Disease
- Standard Disease Name
- addison disease
- MeSH Tree
- No data
- ICD-10
- E27.1
Identifiers
- DO ID
- No data
- MeSH ID
- D000224
- OMIM ID
- 240200|300371|MTHU006714|MTHU012235|MTHU008541
- UMLS ID
- C0001403
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_02D:A long-standing and persistent diminished production of adrenocortical hormones due to a disorder originating within the adrenal glands.|MSH2017_2016_08_12:An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.|MEDLINEPLUS_20151021:<p>Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make enough of these hormones.</p> <p>A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer.</p> <p>Symptoms include</p> <ul> <li>Weight loss </li> <li>Muscle weakness </li> <li>Fatigue that gets worse over time </li> <li>Low blood pressure </li> <li>Patchy or dark skin </li> </ul> <p>Lab tests can confirm that you have Addison disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have Addison disease, you should carry an emergency ID. It should say that you have the disease, list your medicines and say how much you need in an emergency.</p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:Insufficient production of steroid hormones (primarily cortisol) by the adrenal glands as a result of a primary defect in the glands themselves. [HPO:probinson]|CSP2006:disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin; due to tuberculosis or autoimmune induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol.
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Related Targets
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