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KRT25
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- Entity Type
- Diseases
- Relation Groups
- 1
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- 5
Basic Information
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Core Information
- Disease Name
- Hypotrichosis 13
- Standard Disease Name
- hypotrichosis 13
- MeSH Tree
- No data
- ICD-10
- D3A.00
Identifiers
- DO ID
- No data
- MeSH ID
- D002276
- OMIM ID
- MTHU018346
- UMLS ID
- C0007095
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NCI-GLOSS_1602D:A slow-growing type of tumor usually found in the gastrointestinal system (most often in the appendix), and sometimes in the lungs or other sites. Carcinoid tumors may spread to the liver or other sites in the body, and they may secrete substances such as serotonin or prostaglandins, causing carcinoid syndrome.|NCI2016_CDISC_1602D:A neuroendocrine neoplasm arising from enterochromaffin cells in the gastrointestinal tract and (less common) the bronchi with undetermined malignancy status.|NCI2016_02D:A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.|MSH2017_2016_08_12:A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)|MEDLINEPLUS_20151021:<p>Carcinoid tumors are rare, slow-growing cancers. They usually start in the lining of the digestive tract or in the lungs. They grow slowly and don't produce symptoms in the early stages. As a result, the average age of people diagnosed with digestive or lung carcinoids is about 60. </p> <p>In later stages the tumors sometimes produce hormones that can cause carcinoid syndrome. The syndrome causes flushing of the face and upper chest, diarrhea, and trouble breathing. </p> <p>Surgery is the main treatment for carcinoid tumors. If they haven't spread to other parts of the body, surgery can cure the cancer. </p>|HPO2016_07_04:A tumor formed from the endocrine (argentaffin) cells of the mucosal lining of a variety of organs including the stomach and intestine. These cells are from neuroectodermal origin. [HPO:sdoelkens]|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract|CHV2011_02:A usually small, slowly growing tumor usually found in gastrointestinal tract
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