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Diseases

22Q11 Deletion Syndrome

22q11 deletion syndrome

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
22Q11 Deletion Syndrome
Standard Disease Name
22q11 deletion syndrome
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D058165
OMIM ID
No data
UMLS ID
C2936346
HPO ID
No data

Description and Extensions

Description
MSH2017_2016_08_12:Condition with a variable constellation of phenotypes due to deletion polymorphisms at chromosome location 22q11. It encompasses several syndromes with overlapping abnormalities including the DIGEORGE SYNDROME, VELOCARDIOFACIAL SYNDROME, and CONOTRUNCAL AMOMALY FACE SYNDROME. In addition, variable developmental problems and schizoid features are also associated with this syndrome. (From BMC Med Genet. 2009 Feb 25;10:16) Not all deletions at 22q11 result in the 22q11deletion syndrome.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
02
CRKL
CRK like proto-oncogene, adaptor protein
CRK like proto-oncogene, adaptor protein
04
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
gamma-aminobutyric acid type B receptor subunit 1