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ADIPOQ
No data
- Entity Type
- Diseases
- Relation Groups
- 1
- Relation Preview
- 8
Basic Information
Grouped by core information, identifiers, and descriptions.
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Core Information
- Disease Name
- Crohn Disease
- Standard Disease Name
- crohn disease
- MeSH Tree
- No data
- ICD-10
- K50.90|K50|K50.9
Identifiers
- DO ID
- No data
- MeSH ID
- D003424
- OMIM ID
- 266600
- UMLS ID
- C0010346
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NICHD_1602D:A chronic, transmural inflammation that can affect any location along the gastrointestinal tract.|NCI2016_NCI-GLOSS_1602D:A condition in which the gastrointestinal tract is inflamed over a long period of time. Crohn disease usually affects the small intestine and colon. Symptoms include fever, diarrhea, stomach cramps, vomiting, and weight loss. Crohn disease increases the risk of colorectal cancer and small intestine cancer. It is a type of inflammatory bowel disease (IBD).|NCI2016_02D:A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.|MSH2017_2016_08_12:A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.|MEDLINEPLUS_20151021:<p>Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. Crohn's can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum.</p> <p>The cause of Crohn's disease is unknown. It may be due to an abnormal reaction by the body's immune system. It also seems to run in some families. It most commonly starts between the ages of 13 and 30.</p> <p>The most common symptoms are pain in the abdomen and diarrhea. Other symptoms include</p> <ul> <li>Bleeding from the rectum</li> <li>Weight loss</li> <li>Fever</li> </ul> <p>Your doctor will diagnose Crohn's disease with a physical exam, lab tests, imaging tests, and a colonoscopy.</p> <p>Crohn's can cause complications, such as <a href='https://www.nlm.nih.gov/medlineplus/intestinalobstruction.html'>intestinal blockages</a>, ulcers in the intestine, and problems getting enough nutrients. People with Crohn's can also have joint pain and skin problems. Children with the disease may have growth problems.</p> <p>There is no cure for Crohn's. Treatment can help control symptoms, and may include medicines, nutrition supplements, and/or surgery. Some people have long periods of remission, when they are free of symptoms.</p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:A chronic granulomatous inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea which may be bloody, vomiting, or weight loss, but may also cause complications outside of the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration. Crohn's disease is thought to be an autoimmune disease, in which the body's immune system attacks the gastrointestinal tract, causing inflammation. [HPO:sdoelken]|CSP2006:gastrointestinal disorder characterized by chronic inflammatory infiltrates, fibrosis affecting all layers of the serosa, and development of noncaseating granulomas; most common site of involvement is the terminal ileum with the colon as the second most common.
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