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Diseases

Ependymoma

ependymoma

Entity Type
Diseases
Relation Groups
2
Relation Preview
16

Basic Information

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Core Information

Disease Name
Ependymoma
Standard Disease Name
ependymoma
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D004806
OMIM ID
MTHU008962|137800|MTHU036794
UMLS ID
C0014474
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:A malignant neoplasm arising from ependymal cells that line the ventricles of the brain and the central canal of the spinal cord.|NCI2016_NCI-GLOSS_1602D:A type of brain tumor that begins in cells lining the spinal cord central canal (fluid-filled space down the center) or the ventricles (fluid-filled spaces of the brain). Ependymomas may also form in the choroid plexus (tissue in the ventricles that makes cerebrospinal fluid).|NCI2016_CDISC_1602D:A neoplasm of ependymal origin, for which the malignancy status has not been established.|NCI2016_02D:A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)(from WHO)|MSH2017_2016_08_12:Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)|HPO2016_07_04:The presence of an ependymoma of the central nervous system. [HPO:probinson]|CSP2006:gliomas derived from ependymocytes that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults; may arise from any level of the ventricular system or central canal of the spinal cord; intracranial ependymomas most frequently originate in the fourth ventricle and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes; spinal ependymomas are usually benign papillary or myxopapillary tumors.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
01
ASAH1
N-acylsphingosine amidohydrolase 1
N-acylsphingosine amidohydrolase 1
03
CRHR1
corticotropin releasing hormone receptor 1
corticotropin releasing hormone receptor 1