Diseases

Hepatoblastoma

hepatoblastoma

Basic Information

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Description: NCI2016_NICHD_1602D:A malignant neoplasm of embryonal origin arising within the liver|NCI2016_NCI-GLOSS_1602D:A type of liver tumor that occurs in infants and children.|NCI2016_CDISC_1602D:A malignant liver neoplasm composed of immature hepatocytic elements.|NCI2016_02D:A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.|MSH2017_2016_08_12:A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)|HPO2016_07_04:A kind of neoplasm of the liver that originates from immature liver precursor cells and macroscopically is composed of tissue resembling fetal or mature liver cells or bile ducts. [eMedicine:986802, HPO:probinson]|CSP2006:malignant liver neoplasm occurring in children and composed of tissue resembling fetal or mature liver cells or bile ducts.

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target disease8 Targets

actin beta

AKT serine/threonine kinase 1

cell division cycle 25C