Skip to main content
Diseases

Polycystic Kidney Diseases

polycystic kidney diseases

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

Quick relations do not expand inferred candidates by default. Load path-derived ingredients or herbs when needed.

Core Information

Disease Name
Polycystic Kidney Diseases
Standard Disease Name
polycystic kidney diseases
MeSH Tree
No data
ICD-10
Q61.3

Identifiers

DO ID
No data
MeSH ID
D007690
OMIM ID
MTHU017769
UMLS ID
C0022680
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:An inherited form of kidney disease characterized by multiple renal cysts.|NCI2016_02D:A usually autosomal dominant and less frequently autosomal recessive genetic disorder characterized by the presence of numerous cysts in the kidneys leading to end-stage renal failure. The autosomal dominant trait is associated with abnormalities on the short arm of chromosome 16. Symptoms in patients with the autosomal dominant trait usually appear at middle age and include abdominal pain, hematuria, and high blood pressure. Patients may develop brain aneurysms and liver cysts. Patients with the autosomal recessive trait present with progressive renal failure early in life and symptoms resulting from hepatic fibrosis. The autosomal recessive trait is associated with abnormalities of chromosome 6. Polycystic kidney disease may also result as a side effect in patients on renal dialysis.|MSH2017_2016_08_12:Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.|HPO2016_07_04:The presence of multiple cysts in both kidneys. [HPO:probinson]|CSP2006:hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed cysts within the kidney; there is an autosomal recessive form appearing in childhood and a later appearing autosomal dominant form; a similar acquired disease sometimes accompanies end-stage renal disease.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
04
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
eukaryotic translation initiation factor 4E binding protein 1
06
MAP2K5
mitogen-activated protein kinase kinase 5
mitogen-activated protein kinase kinase 5