Diseases

Bronchiolitis Obliterans Organizing Pneumonia

bronchiolitis obliterans organizing pneumonia

Entity Type: Diseases
Relation Groups: 3
Relation Preview: 24

Basic Information

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Core Information

Disease Name: Bronchiolitis Obliterans Organizing Pneumonia
Standard Disease Name: bronchiolitis obliterans organizing pneumonia
MeSH Tree: No data
ICD-10: J84.116

Identifiers

DO ID: No data
MeSH ID: D018549
OMIM ID: MTHU044482
UMLS ID: C0242770
HPO ID: No data

Description and Extensions

Description: NCI2016_02D:A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.(MeSH)|MSH2017_2016_08_12:An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.|HPO2016_07_04:Bronchiolitis obliterans organizing pneumonia (BOOP) is and interstitial lung abnormalitiy characterized histopathologically by plugs of granulation tissue lying within small airways, alveolar ducts, and alveoli and by chronic inflammatory cell infiltration in alveolar walls. Patients with BOOP generally present with subacute illness, including shortness of breath, fever, malaise, and weight loss. [DDD:tkuijpers, HPO:probinson, pmid:20858818]

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