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Diseases

Paraganglioma

paraganglioma

Entity Type
Diseases
Relation Groups
2
Relation Preview
16

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Paraganglioma
Standard Disease Name
paraganglioma
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D010235
OMIM ID
MTHU015031|MTHU004448|168000|602690
UMLS ID
C0030421
HPO ID
No data

Description and Extensions

Description
NCI2016_NCI-GLOSS_1602D:A rare, usually benign tumor that develops from cells of the paraganglia. Paraganglia are a collection of cells that came from embryonic nervous tissue, and are found near the adrenal glands and some blood vessels and nerves. Paragangliomas that develop in the adrenal gland are called pheochromocytomas. Those that develop outside of the adrenal glands near blood vessels or nerves are called glomus tumors or chemodectomas.|NCI2016_CDISC_1602D:A neoplasm arising from paraganglia located along nerves composed of neoplastic neuroectodermal chromaffin cells, for which the malignancy status has not been established.|NCI2016_02D:A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases.|MSH2017_2016_08_12:A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)|HPO2016_07_04:A carotid body tumor (also called paraganglionoma or chemodectoma) is a tumor found in the upper neck at the branching of the carotid artery. They arise from the chemoreceptor organ (paraganglion) located in the adventitia of the carotid artery bifurcation. [HPO:probinson]
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
01
BRAF
B-Raf proto-oncogene, serine/threonine kinase
B-Raf proto-oncogene, serine/threonine kinase