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Diseases

Pituitary-Dependent Cushing'S Disease

pituitary-dependent cushing's disease

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

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Core Information

Disease Name
Pituitary-Dependent Cushing'S Disease
Standard Disease Name
pituitary-dependent cushing's disease
MeSH Tree
No data
ICD-10
E24.0

Identifiers

DO ID
No data
MeSH ID
D047748
OMIM ID
MTHU016860|219090
UMLS ID
C0221406
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:Cushing's syndrome due to abnormally high secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland.|NCI2016_NCI-GLOSS_1602D:A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the body. In Cushing disease, this happens when an adenoma (benign tumor) in the pituitary gland makes too much adrenocorticotropic hormone (ACTH). This causes the adrenal gland to make too much cortisol. Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, and weight gain, especially in the abdomen.|NCI2016_02D:Cushing's syndrome due to abnormally high secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland.(NICHD)|MSH2017_2016_08_12:A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
Related

Direct relations and traceable candidates grouped by relation type.

Related Targets

target disease8 Targets
03
BRAF
B-Raf proto-oncogene, serine/threonine kinase
B-Raf proto-oncogene, serine/threonine kinase
05
CRHR1
corticotropin releasing hormone receptor 1
corticotropin releasing hormone receptor 1
06
NR3C1
nuclear receptor subfamily 3 group C member 1
nuclear receptor subfamily 3 group C member 1