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Diseases

Paraneoplastic Cerebellar Degeneration

paraneoplastic cerebellar degeneration

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Entity Type
Diseases
Relation Groups
3
Relation Preview
24

Basic Information

Grouped by core information, identifiers, and descriptions.

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Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.

Core Information

Disease Name
Paraneoplastic Cerebellar Degeneration
Standard Disease Name
paraneoplastic cerebellar degeneration
MeSH Tree
No data
ICD-10
No data

Identifiers

DO ID
No data
MeSH ID
D020362
OMIM ID
No data
UMLS ID
C0393534
HPO ID
No data

Description and Extensions

Description
NCI2016_02D:A rare, immune-mediated disorder characterized by cerebellar degeneration due to the presence of an often undetected malignancy (usually carcinoma or lymphoma) in an anatomic site other than the cerebellum. Signs and symptoms include progressive ataxia, dysarthria, and nystagmus.|MSH2017_2016_08_12:Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)