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Diseases

Anencephaly

anencephaly

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Anencephaly
Standard Disease Name
anencephaly
MeSH Tree
No data
ICD-10
Q00.0

Identifiers

DO ID
No data
MeSH ID
D000757
OMIM ID
MTHU011716|206500
UMLS ID
C0002902
HPO ID
No data

Description and Extensions

Description
NCI2016_CDISC_1602D:Absence of the cranial region of the head, with the brain absent or reduced. (Makris S, Solomon HM, Clark R, Shiota K, Barbellion S, Buschmann J, Ema M, Fujiwara M, Grote K, Hazelden KP, Hew KW, Horimoto M, Ooshima Y, Parkinson M, Wise LD. Terminology of developmental abnormalities in common laboratory mammals (Version 2). Part B. Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):227-327.)|NCI2016_02D:A rare neural tube defect during pregnancy, resulting in the absence of a large portion of the brain and skull in the fetus.|MSH2017_2016_08_12:A malformation of the nervous system caused by failure of the anterior neuropore to close. Infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level. The skull is only partially formed but the eyes are usually normal. This condition may be associated with folate deficiency. Affected infants are only capable of primitive (brain stem) reflexes and usually do not survive for more than two weeks. (From Menkes, Textbook of Child Neurology, 5th ed, p247)|CSP2006:congenital malformation of the nervous system caused by failure of the anterior neuropore to close; infants are born with intact spinal cords, cerebellums, and brainstems, but lack formation of neural structures above this level; the skull is only partially formed but the eyes are usually normal; affected infants are only capable of primitive reflexes and usually do not survive for more than two weeks; complete absence of the brain is rare.
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