01
Diseases
Iron-Refractory Iron Deficiency Anemia
iron-refractory iron deficiency anemia
- Entity Type
- Diseases
- Relation Groups
- 1
- Relation Preview
- 8
Basic Information
Grouped by core information, identifiers, and descriptions.
Quick relations do not expand inferred candidates by default. Load path-derived ingredients or herbs when needed.
Core Information
- Disease Name
- Iron-Refractory Iron Deficiency Anemia
- Standard Disease Name
- iron-refractory iron deficiency anemia
- MeSH Tree
- No data
- ICD-10
- D74|D74.9
Identifiers
- DO ID
- No data
- MeSH ID
- D008708
- OMIM ID
- MTHU039706
- UMLS ID
- C0025637
- HPO ID
- No data
Description and Extensions
- Description
- NCI2016_NCI-GLOSS_1602D:A condition in which a higher-than-normal amount of methemoglobin is found in the blood. Methemoglobin is a form of hemoglobin that cannot carry oxygen. In methemoglobinemia, tissues cannot get enough oxygen. Symptoms may include headache, dizziness, fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, loss of muscle coordination, and blue-colored skin. Methemoglobinemia can be caused by injury or being exposed to certain drugs, chemicals, or foods. It can also be an inherited condition.|NCI2016_02D:An inherited or acquired condition characterized by abnormally increased levels of methemoglobin in the blood.|MSH2017_2016_08_12:The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)|HPO2016_07_04:Abnormally increased levels of Methemoglobinemia in the blood. In this form of hemoglobin, there is an oxidized ferric iron (Fe +3) rather than the reduced ferrous form (Fe 2+) that is normally found in hemoglobin. Methemoglobin has a reduced affinity for oxygen, resulting in a reduced ability to release oxygen to tissues. [HPO:probinson]