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Core Information
Disease Name
Long Qt Syndrome
Standard Disease Name
long qt syndrome
MeSH Tree
No data
ICD-10
I45.81
Identifiers
DO ID
No data
MeSH ID
D008133
OMIM ID
MTHU039019
UMLS ID
C0023976
HPO ID
No data
Description and Extensions
Description
NCI2016_NICHD_1602D:A syndrome characterized by a propensity to develop life-threatening arrhythmias usually in the context of a prolonged corrected QT interval.|NCI2016_CDISC_1602D:Long QT Syndrome includes prolongation of the corrected QT interval beyond 440 ms for adult males, 460 ms for adult females and 50 ms in the presence of ventricular depolarization abnormalities (i.e., bundle branch blocks or IVCB more than 120 ms. A normal QT interval in a resting ECG with a failure to shorten with an increase in heart rate qualifies as Long QT Syndrome.|NCI2016_02D:A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death.|MSH2017_2016_08_12:A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.|CSP2006:prolongation of Q-T interval combined with torsades de pointes and manifests as several different forms; may be acquired or congenital; may lead to serious arrhythmia and sudden cardiac death.
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