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Diseases

Polymyositis

polymyositis

Entity Type
Diseases
Relation Groups
1
Relation Preview
8

Basic Information

Grouped by core information, identifiers, and descriptions.

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Core Information

Disease Name
Polymyositis
Standard Disease Name
polymyositis
MeSH Tree
No data
ICD-10
M33.2

Identifiers

DO ID
No data
MeSH ID
D017285
OMIM ID
MTHU037341
UMLS ID
C0085655
HPO ID
No data

Description and Extensions

Description
NCI2016_NICHD_1602D:An inflammatory disorder affecting the muscles. It presents with symmetrical proximal muscle weakness. Complications include distal weakness, thickening skin of hands and interstitial lung disease. Juvenile polymyositis is a rare early onset form of the disease.|NCI2016_NCI-GLOSS_1602D:An inflammatory disease of the muscles closest to the center of the body. It causes weakness, inability to stand, climb stairs, lift, or reach. It may also cause muscle pain and difficulty swallowing, and may affect the lungs and heart. Having polymyositis increases the risk of certain types of cancer.|NCI2016_02D:An idiopathic inflammatory disorder affecting the muscles. It presents with symmetrical proximal muscle weakness and elevated skeletal muscle enzymes.|MSH2017_2016_08_12:Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)|CSP2006:inflammation of a number of voluntary muscles simultaneously.
Related

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Related Targets

target disease8 Targets
08
SCN4A
sodium voltage-gated channel alpha subunit 4
sodium voltage-gated channel alpha subunit 4