Diseases

Immune Thrombocytopenic Purpura

immune thrombocytopenic purpura

Entity Type: Diseases
Relation Groups: 3
Relation Preview: 24

Basic Information

Grouped by core information, identifiers, and descriptions.

Current candidates are inferred from disease-target-ingredient-herb paths and do not represent a formal recommendation ranking.

Core Information

Disease Name: Immune Thrombocytopenic Purpura
Standard Disease Name: immune thrombocytopenic purpura
MeSH Tree: No data
ICD-10: D80.3

Identifiers

DO ID: No data
MeSH ID: D017099
OMIM ID: MTHU012163|MTHU006900
UMLS ID: C0162539
HPO ID: No data

Description and Extensions

Description: NCI2016_02D:A classification of dysgammaglobulinemias characterized by low or undetectable serum levels of one of the four immunoglobulin class G (IgG) subclasses. Selective IgG1 deficiency is rare and primarily decreases the immune response to bacterial protein antigens. Selective IgG2 deficiency is the most common subclass deficiency among children and primarily leads to an inadequate response to bacterial polysaccharide antigens. Selective IgG3 deficiency is the most common subclass deficiency among adults and also primarily lowers the response to bacterial proteins. Selective IgG4 deficiency may be a clinically insignificant developmental variant, as IgG4 is a subclass that is virtually undetectable until the end of the first decade of life. Low levels of any IgG subclass will reduce the immune system's effectiveness and thus the clinical presentation of these diseases is usually recurrent infection, particularly by encapsulated bacteria.|NCI2016_02D:A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of immunoglobulin class G (IgG). Deficiencies of IgG present variably according to subclass. IgG deficiencies are typically relative among subclasses and not absolute. Thus even with a given selective IgG subclass deficiency, total IgG levels may still fall within normal range. The clinical course and prognosis is dependent upon the severity of the deficiency and associated morbidity.|MSH2017_2016_08_12:A dysgammaglobulinemia characterized by a deficiency of IMMUNOGLOBULIN G.|HPO2016_07_04:An abnormally decreased level of immunoglobulin IgG in blood. [HPO:probinson]

Direct relations and traceable candidates grouped by relation type.