Diseases

Smallpox

smallpox

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Entity Type: Diseases
Relation Groups: 1
Relation Preview: 8

Basic Information

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Core Information

Disease Name: Smallpox
Standard Disease Name: smallpox
MeSH Tree: No data
ICD-10: B03

Identifiers

DO ID: No data
MeSH ID: D012899
OMIM ID: No data
UMLS ID: C0037354
HPO ID: No data

Description and Extensions

Description: MSH2017_2016_08_12:An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed)|MEDLINEPLUS_20151021:Smallpox is a disease caused by the Variola major virus. Some experts say that over the centuries it has killed more people than all other infectious diseases combined. Worldwide immunization stopped the spread of smallpox three decades ago. The last case was reported in 1977. Two research labs still keep small amounts of the virus. Experts fear <a href='https://www.nlm.nih.gov/medlineplus/biodefenseandbioterrorism.html'>bioterrorists</a> could use the virus to spread disease. Smallpox spreads very easily from person to person. Symptoms are flu-like. They include <ul> <li>High fever</li> <li>Fatigue</li> <li>Headache</li> <li>Backache</li> <li>A rash with flat red sores</li> </ul> There is no treatment. Fluids and medicines for pain or fever can help control symptoms. Most people recover, but some can die. Those who do recover may have severe scars. The U.S. stopped routine smallpox vaccinations in 1972. Military and other high-risk groups continue to get the vaccine. The U.S. has increased its supply of the vaccine in recent years. The vaccine makes some people sick, so doctors save it for those at highest risk of disease. NIH: National Institute of Allergy and Infectious Diseases

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Related Targets

target disease8 Targets

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CDK5R1

cyclin dependent kinase 5 regulatory subunit 1